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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ANAPC1
All Species:
4.55
Human Site:
S143
Identified Species:
9.09
UniProt:
Q9H1A4
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H1A4
NP_073153.1
1944
216500
S143
D
K
S
E
K
A
Y
S
S
N
E
V
E
K
C
Chimpanzee
Pan troglodytes
XP_515601
1394
155989
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_532958
1943
216470
S143
D
K
S
E
K
A
Y
S
S
N
E
V
E
K
C
Cat
Felis silvestris
Mouse
Mus musculus
P53995
1944
216068
K143
D
K
S
E
K
I
Y
K
S
H
E
L
E
K
C
Rat
Rattus norvegicus
NP_001101241
1944
216060
K143
D
K
S
E
K
I
Y
K
S
H
E
L
E
K
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_419303
1945
216100
G144
K
S
D
K
A
D
G
G
K
E
I
V
Q
K
C
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001921168
1979
220132
N143
K
D
G
K
N
L
Y
N
F
D
V
V
E
Q
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_573025
2030
227256
P188
Q
L
K
A
A
V
H
P
D
D
D
H
L
T
A
Honey Bee
Apis mellifera
XP_001122449
1939
218025
D128
R
K
E
I
D
E
E
D
Y
D
K
T
I
E
C
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001202400
910
100394
Poplar Tree
Populus trichocarpa
XP_002312165
1929
212815
V128
I
Y
N
I
S
G
E
V
V
S
I
P
I
P
C
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_196175
1678
186257
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
71.5
N.A.
97.3
N.A.
92.1
92.9
N.A.
N.A.
81.7
N.A.
66
N.A.
33.6
38
N.A.
25.2
Protein Similarity:
100
71.5
N.A.
98.5
N.A.
96
96.5
N.A.
N.A.
90.2
N.A.
79
N.A.
52.2
59.1
N.A.
33.8
P-Site Identity:
100
0
N.A.
100
N.A.
73.3
73.3
N.A.
N.A.
20
N.A.
20
N.A.
0
13.3
N.A.
0
P-Site Similarity:
100
0
N.A.
100
N.A.
86.6
86.6
N.A.
N.A.
33.3
N.A.
46.6
N.A.
20
33.3
N.A.
0
Percent
Protein Identity:
28.5
N.A.
N.A.
27.2
N.A.
N.A.
Protein Similarity:
47
N.A.
N.A.
45.8
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
20
N.A.
N.A.
0
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
17
17
0
0
0
0
0
0
0
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
59
% C
% Asp:
34
9
9
0
9
9
0
9
9
25
9
0
0
0
0
% D
% Glu:
0
0
9
34
0
9
17
0
0
9
34
0
42
9
0
% E
% Phe:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% F
% Gly:
0
0
9
0
0
9
9
9
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
9
0
0
17
0
9
0
0
0
% H
% Ile:
9
0
0
17
0
17
0
0
0
0
17
0
17
0
0
% I
% Lys:
17
42
9
17
34
0
0
17
9
0
9
0
0
42
0
% K
% Leu:
0
9
0
0
0
9
0
0
0
0
0
17
9
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
9
0
9
0
0
9
0
17
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
9
0
0
0
9
0
9
0
% P
% Gln:
9
0
0
0
0
0
0
0
0
0
0
0
9
9
0
% Q
% Arg:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
9
34
0
9
0
0
17
34
9
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
9
0
9
9
% T
% Val:
0
0
0
0
0
9
0
9
9
0
9
34
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
0
0
0
0
42
0
9
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _